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 INFORMATION
The foundation of the vaccines against VPH is the same that other vaccines that they protect against other viral infections. That is to say that it is a question of stimulating the immune system against certain proteins similar to the viruses that are not infectious but that produce an antibodies answer against the human papilloma virus. These proteins are the same or similar ones to those who are in the viruses of the papilloma humanly and for it the immune answer, of the vaccinated individual, already has a memory to eliminate these viruses, which is the foundation of all the vaccines.
On having had a prepared immune system, the infection by the virus VPH is eliminated precozmente and does not give place to chronic infections and hence cancerous modifications in the cells of the organism.
It was not possible to have demonstrated that the cancerous changes are prepared by the vaccines, only they prepare of the infection.
TYPES OF VACCINES
The already existing vaccines prepare of the infections of the types of VPH 16 and 18, which are two types of VPH of "high risk" that cause the majority (70 %) of the cervical cancers. Also also there are vaccines against the types 6 and 11 of VPH, which cause 90 % of the genital warts. His efficacy is radical, they have demonstrated the prevention of almost 100 % of the precancerous changes, at least for 4 years after the vaccination.
- Gardasil ® (Sanofi Synthelabo/Merck). It is a vaccine against the types of VPH, 6, 11, 16 and 18. Gardasil is administered in a series of three intramuscular injections in 6 months.
- Cervarix ®, (GSK). It is a vaccine against the types of VPH, 16 and 18. The rules are similar to the previous one, three doses in 6 meses. /
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These vaccines do not prepare against other types of VPH for it there is at least a third part of the viruses of the VPH that are not covered with these vaccines. For it it is recommended to keep on doing, in spite of being vaccinated, of gynecological periodic reviews and of cytologies of Papanicolau to the women.
So that his efficacy is tangible massive vaccinations must be done in the adolescence. It is recommended to put it before the beginning of the sexual activity between 9 and 26 years of age. The problem is the cost that can range between 300 to 500 Euros for person.
They have no side effects beyond the proper inflammatory local reactions the first days.
His demonstrated efficacy is 4 years, from which one is considering to do reinforcement revaccinations.
The efficacy of the vaccine is not known in already infected persons or with demonstrated changes of the cervical mucous membrane, that is to say with the chronic infection and alterations precancerous demonstrated previously.
TO SEE ALSO
Virus of the Papilloma Humanized VPH
Cytology
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