The most frequent symptomatology is the morning sickness and the vomiting. It usually present in the beginning of the gestation and tends to diminish the same way as advances. Topcoat happens in the tomorrow. In 50 % of the cases they accompany themselves of vomiting. 0,35 % evolves towards a picture of hiperemesis gravídica, characterized by uncoercible vomiting and affectation of the general state.

To be able to avoid it there are recommended frequent unexploits of small quantities of food and to have breakfast copiously. Small carbohydrates quantities must be recommended as well as have sponge cake or cookies in the bedside table to take them in the bed when he wakes up in the morning, until the morning nauseating sensations autolimit themselves. There seems beneficial the increase of contribution of carbohydrates and the decrease of the fats, as well as to avoid the food of strong or penetrating smell.

The antiemetic ones seem to reduce the frequency of the morning sickness in the initial phase of the pregnancy. Scarce information about the side effects exists in the fetus. The most effective medicine is the Piridoxina (mg 3 times a day) it limits the intensity of the morning sickness to dose of 10-25 and it is perhaps that of less side effects. The medicine most used in Spain is the Cariban ®, an association of the antihistamine doxilamina with piridoxina, the habitual rule is to initiate the treatment with 1 tablet before going to bed being able to increase the dose to 3 tablets a day. It is the only one that it has demonstrated, by means of clinical essays, not to produce increase in the malformations risk.