The crises of sharp drop or arthritis gouty talk each other with anti-inflammatory not esteroideos (AINE), being often necessary to administer high doses. Although probably in the treatment of the sharp drop they all are effective AINE, the indometacina is usually used.
The sharp drop also can talk each other by means of colchicina if the stomach tolerates it.

The medicines hipouricemiantes, that is to say, that lower the uric acid, like the alopurinol or the probenecid worsen the episodes of sharp drop and they must never be administered during a sharp crisis. Generally it talks each other with colchicina, anti-inflammatory or the two simultaneously. The colchicina has the disadvantage of producing diarrhea and anti-inflammatory stomach inconveniences.

Once controlled the arthritis sharp it is necessary to raise the need or not of diminishing the values of uric acid with medicines. In this paragraph we will check only the medicines.

There are two classes of useful medicines:

• Those who prevent from forming the uric acid: Alopurinol.
• Those who favor his elimination for the kidney: Probenecid, sulfinpirazona.

On having initiated the treatment, with some of these medicines it is possible to provoke the appearance of an attack of drop, therefore it usually to associate at first the treatment that they diminish the uric acid with the colchicina to low doses like prevention of these attacks of arthritis.

The doses that are used in every patient are going to be variables, but it is always necessary to look for the necessary minimal dose to support the uric acid in normal numbers. This has to realize analysis at the beginning of the treatment with relative frequency, first to fit the dose to the required minim and later to verify that undesirable effects due to the medication do not exist.

The treatment of the drop is very long and generally for the whole life, what must be comprised by the patients, but in some occasions on having corrected factors that they contribute to the hiperuricemia as the obesity and to eliminate the alcohol and to continue a strict diet, the patients can limit to the minimum the medicines.
The persons with hiperuricemia asymptomatic must not be treated unless the numbers of uric acid are much over the normal values or his elimination for the kidney is very important, since in these cases the possibilities of developing attacks of arthritis or nephritic colics are very high. In the rest of the patients, since the risk of developing the illness is not very big they are not going to talk each other.

The election of the treatment depends on the characteristics of every patient. The alopurinol is indicated in the patients with nefrolitiasis (stones in the kidney), tofos gouty (nodules in the joints) or nefropatía gouty, as well as also in those who present a congenital uric acid hyperproduction.