PHOTOSENSIBILITY

The photosensibility reactions are those produced important and abnormal clinical pictures unleashed or aggravated by the exhibition to the light, generally solar. In contrast to the fototoxia, the skin reacts of exaggerated form and does not reproduce only an increase of the tonality, but there appear injuries of eczema, formation of blisters, etc...

FOTOTÓXIA

It is the increase of absorption of the solar light for the capture or contact of medicines or chemicals, or sometimes for alterations of the metabolism of the persons or in certain illnesses. The injuries that take place are the same that the solar exhibition produces only that more intense and that appear with minor exhibition time.

Fototoxia induced by medicines.

The most implied medicines are:
acid nalidíxico, amiodarona, captopril, clorotiacidas, etretinato, fenotiacinas (clorpromacina, prometacina, tioridacina, etc.), furosemida, griseofulvina, naproxeno, piracinamida, piroxicam, psoralenos or furocumarinas, sulfonamidas, tetraciclinas (especially doxiciclina and dimetilclortetraciclina), and derivatives of the tar.

On having eliminated the responsible medicine, the injuries yield.

Photosensibility induced by medicines.

The present medicine in the skin absorbs light (especially beams GRAPE) and forms a photoproduct that joins the proteins to form a finished antigen, which produces the allergic reaction. The injuries are of eczema, with itch vesicles and exudation deaparición in areas exposed to the solar light, although if the exhibition persists extieden to the whole body. The photoallergy can persist for months or years in spite of not existing I contact with the responsible substance.

• Causers of general administration:
• fenotiacinas
• sulfonamidas
• group PARA
• Of local administration:
• salicilanilidas halogenadas (deodorants and soaps)
• PABA and derivatives (solar filters)
• cinamatos and benzofenonas (solar filters)
• benzocaína
• neomicina
• musk perfume
• tioureas presents in the neopreno

For the diagnosis tests are used epicutáneas and fotopatch test, which is the reproduction of the application, to small doses of the suspicious product, in the skin during 24 hours and exhibition to a GRAPE lamp to different bogeys to reproduce the eczema injury.

PHOTOSENSITIVE ALLERGY FOR PLANTS (Fitofotodermatitis)

It is a dermatitis caused by contact with plants and exhibition to the solar light. There takes place a photopoisonous or photoallergic reaction caused by substances fotosensibilizantes (furocumarinas), present in diverse plants.

Producing fitofotodermatitis plants

Rutáceas: Lima, orange, orange embitters, lemon, bergamota, common rue.
Umbelíferas: Parsley, chervil, celery, parsnip, fennel, dill, carrots,
Composed: Yarrow, aquílea and manzanilla
Cruciferous: Mustard
Moráceas: Fig trees (only sheet and stem)
Ranunculáceas: Ranunculus
Rosy: Agrimony
Leguminous plants: Vetches
Hiperáceas: Grass of Saint John

It can appear at any age and race. The most affected professions are a gardening, gardening, flower growing, agriculture, etc. It is more frequent in summer. In the sharp phase it appears eritema, vesicles and blisters with itching, but without a dermatitis eccematosa.
A residual pigmentation can exist with artificial forms (lines, etc., depending on some work realized in the exterior). The injuries are distributed in contact areas, especially in the arms and the legs. The sharp eruption yields spontaneously, but the hyperpigmentation can persist weeks.

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