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ANALYSIS OF LDH IN WHEY
DENOMINATION DEFINITION STUDIED SECURING RISKS VALUE DIAGNOSIS TO SEE TO CONSULT

DENOMINATION

  • Lactato deshidrogenasa,
  • Lactic deshidrogenasa.

DEFINITION

The LDH is an enzyme that is in many textiles of the body, but his presence is major in the heart, liver, kidneys, muscles, red globules, in the brain and in the lungs.

His function is to interturn the piruvato and the lactato. Into the muscular exercise the muscular cells transform the glucose in lactato, the lactato is liberated to the blood, and can be gathered by the liver that transforms it again into glucose that spills to the blood so that it could turn to use like energy for the textiles.

The LDH has one big isoenzimas variety with light differences in his structure, which suggest different origins for every textile (LDH1 of the heart, LDH2 of the system reticulum endotelial, the LDH3 of the lungs, the LDH4 of the kidneys, the LDH5 of the liver and muscle).

The LDH2 in normal persons is the biggest constituent of the entire LDH.

WHY IS THE ANALYSIS REALIZED?

It is used to evaluate the presence of injuries in the textiles.

When some textile that LDH contains is injured person spills more LDH quantity to the blood for it turns out to be raised before any injury of heart, liver, kidneys, muscle, etc...

When there is a problem of isquemia in the myocardium with injury of the muscle there appears the LDH risen to 2 days, keeps on rising until the third day and then it returns to the normality to the 5 to 10 days. If the cardiac isquemia has not injured the muscle (infarction) the LDH it turns out to be normal.

PROCEDURE OF SECURING

To realize this analysis to be on an empty stomach is not needed.

The intense physical exercise produces normal increase of the LDH. Some medicines can raise the level of LDH, the alcohol, the anesthetic ones, the aspirin, the clofibrato, etc. And the LDH can diminish the ascorbic acid.

It is possible to realize the capture in an appropriate place (consultation, clinic, hospital) but sometimes it is realized in the proper domicile of the patient.

To realize the capture it is needed of locating an appropriate vein and in general there are used the veins placed in the flexura of the elbow. The person entrusted to take the sample will use sanitary gloves, a needle (with a syringe or pipe of extraction).

It will put a tortor (tape of gum - latex) in the arm so that the veins retain more blood and turn out to be more visible and accessible.

It will clean the area of the prick with an antiseptic one and by means of a palpación it will locate the appropriate vein and will gain access to her with the needle. They will release the tortor.

When the blood flows for the needle the sanitary one will realize an aspiration (by means of the syringe or by means of the application of a pipe with gap).

On having finished the capture, it extracts the needle to itself and the area is pressed with a cotton or similar torunda to favor the coagulation and it will indicate him to itself that flexione the arm and the area pressed with a Band-Aid supports for some hours.

The abstracted blood moves to the analysis laboratory in a special pipe for biochemistry, which contains an anticoagulant product. In general more than 10 milliliters of blood are not usually necessary for a standard battery of biochemical parameters.

PROBLEMS AND POSSIBLE RISKS

  1. The securing by means of a prick of the vein can produce certain pain.
  2. The possible difficulty in finding the appropriate vein can give place to several pricks
  3. Appearance of a haematoma (bruise or cardinal) in the extraction area, is due usually to the fact that the vein has not closed well after the later pressure and blood has kept on going out producing this problem. Type Hirudoid can apply an ointment to itself ® or Trombocid ® in the area.
  4. Inflammation of the vein (phlebitis), sometimes the vein turns out to be shaken, well be for a cause merely physically or why it has become infected. It will have to support the relaxed area a few days and type Hirudoid can apply an ointment to itself ® or Trombocid ® in the area. If the problem persists or appears fever will have to consult it with his doctor.
NORMAL VALUES OF LDH IN WHEY

Normal levels of LDH in adults 100 to 200 UI/L
Normal levels in children younger than 2 years 100 to 250 UI/L
Normal levels in children between 2 and 8 years 60 to 70 UI/L
Normal levels in newborn babies 160 to 450 UI/L

In these values there can be certain differences for the skill or for proper criteria of normality of concrete laboratories, sometimes in the status of values and other times for the units to which one alludes.

EVALUATION OF ABNORMAL RESULTS

The developing LDH levels can indicate:

  • Vascular brain has an accident
  • Anemia hemolítica, megaloblástica, pernicious
  • Muscular damage
  • Autoimmune illnesses
  • Hepatitis, cirrhosis
  • Low blood pressure
  • Myocardium infarction
  • Intestinal infarction
  • Pulmonary infarction, muddle, pneumonia
  • Renal infarction
  • Linfomas
  • Glandular fever
  • Neoplasias
  • Pancreatitis

TO SEE ALSO

WHAT DOCTOR CAN TREAT ME?

To look a specialist Service offered for
Writing: Medical equipment   Update: June, 2009


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