Frequent questions He asks the doctor Beginning  
ANALYSIS OF ISOENZIMAS OF CPK IN WHEY
DENOMINATION DEFINITION STUDIED SECURING RISKS VALUE DIAGNOSIS TO SEE TO CONSULT

DENOMINATION

  • CPK isoenzimas,
  • Isoenzimas of Creatininfosfoquinasa,
  • Isoenzimas of Creatininfosfoquinasa in blood.

DEFINITION

The creatininfosfoquinasa can present to herself in the shape of 3 isoenzimas that differ in his structure. The CPK-1 ó CPK-BB, is the predominant one in the cerebral textile and in the lung. The CPK-2 also called CPK-MB is that of cardiac origin, and the CPK-3 ó CPK-MM that is that of skeletal muscular origin.

WHY IS THE ANALYSIS REALIZED?

The appearance of CPK raised in the whey suggests injuries in the heart in the brain or in the skeletal músclos. Depending on the isoenzima of high CPK we can differ what the affected textile is.

The CPK-MB rises at 3 a.m. at 6 hours and returns to the normality at 12 a.m. at 48 hours after a myocardium infarction. By it sequential measurements are realized to see the evolution.

The CPK-MB usually does not turn out to be high if the thoracic pain is for an angor (angina pectoris) a pulmonary muddle or for a congestive heart failure.

The CPK-BB turns out to be high if there is damage in the cerebral textile or in case of pulmonary infarction for a muddle.

The CPK-MM is the most abundant isoenzima as entire of the CPK in healthy persons, if it rises it owes to injuries of the skeletal msculo or for very intense physical exercise.

PROCEDURE OF SECURING

To realize this analysis to be on an empty stomach is not needed.

They can turn altered the values of CPK isoenzimas if there have been realized intramuscular injections, muscular traumatism, recent interventions of surgery, or intense or long exercise.

There are medicines that the level of the CPK can raise in whey: Anfotericina B, ampicilina, anesthetic, anticoagulants, aspirin, clofibrato, dexametasona, furosemida, morphine.

It is possible to realize the capture in an appropriate place (consultation, clinic, hospital) but sometimes it is realized in the proper domicile of the patient.

To realize the capture it is needed of locating an appropriate vein and in general there are used the veins placed in the flexura of the elbow. The person entrusted to take the sample will use sanitary gloves, a needle (with a syringe or pipe of extraction).

It will put a tortor (tape of gum - latex) in the arm so that the veins retain more blood and turn out to be more visible and accessible.

It will clean the area of the prick with an antiseptic one and by means of a palpación it will locate the appropriate vein and will gain access to her with the needle. They will release the tortor.

When the blood flows for the needle the sanitary one will realize an aspiration (by means of the syringe or by means of the application of a pipe with gap).

On having finished the capture, it extracts the needle to itself and the area is pressed with a cotton or similar torunda to favor the coagulation and it will indicate him to itself that flexione the arm and the area pressed with a Band-Aid supports for some hours.

The abstracted blood moves to the analysis laboratory in a special pipe for biochemistry, which contains an anticoagulant product. In general more than 10 milliliters of blood are not usually necessary for a standard battery of biochemical parameters.

PROBLEMS AND POSSIBLE RISKS

  1. The securing by means of a prick of the vein can produce certain pain.
  2. The possible difficulty in finding the appropriate vein can give place to several pricks
  3. Appearance of a haematoma (bruise or cardinal) in the extraction area, is due usually to the fact that the vein has not closed well after the later pressure and blood has kept on going out producing this problem. Type Hirudoid can apply an ointment to itself ® or Trombocid ® in the area.
  4. Inflammation of the vein (phlebitis), sometimes the vein turns out to be shaken, well be for a cause merely physically or why it has become infected. It will have to support the relaxed area a few days and type Hirudoid can apply an ointment to itself ® or Trombocid ® in the area. If the problem persists or appears fever will have to consult it with his doctor.
NORMAL VALUES OF CPK IN WHEY

Normal levels of isoenzimas CPK in whey:

CPK 1-MM of 0 to 100 % of the CPK
CPK 2-MB of 0 to 5 % of the CPK
CPK 3-BB 0 % of the CPK

In these values there can be very small differences for the skill or for proper criteria of normality of concrete laboratories, sometimes in the status of values and other times for the units to which one alludes.

EVALUATION OF ABNORMAL RESULTS

The developing levels of CPK-1 - Mm in the blood can indicate:

  • Brain cancer
  • Cerebral infarction
  • Electroconvulsión treatments
  • Hemorrhages subaracnoidea
  • Convulsions
  • Pulmonary infarction

The developing levels of CPK-2-MB in the blood can indicate:

  • Ventricular arrhythmias
  • Isquemia or cardiac infarction
  • Electrocution
  • Treatment of cardiac desfibrilación
  • After heart interventions

The developing levels of CPK-3-BB in the blood can indicate:

  • Convulsions
  • Muscular dystrophy
  • Injections mltiples intramuscular
  • Miositis
  • Muscular traumatism
  • After electromiografía (Electromiograma)
  • Rabdomiolisis
  • After surgery
  • After intense exercise

TO SEE ALSO

WHAT DOCTOR CAN TREAT ME?

To look a specialist Service offered for
Writing: Medical equipment   Update: June, 2009


Our Feature links that help to sponsor our site
wire-wrap jewelry , used cars , plastics , toreuse.com , car.auto-moto-blog.co.uk , used cars ,Alveo Drink