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 DENOMINATION
- Determination of the levels of thyroid hormone T4.
DEFINITION
It is an analysis that is realized separately or in a general biochemistry request in the blood. It measures the quantity of thyroid hormone T4 present in the whey.
The tiroxina (T4) is a hormone produced by the gland thyroid gland that regulates the metabolic processes and of the development.
WHY IS THE ANALYSIS REALIZED?
His determination in blood serves to evaluate the function of the gland thyroid gland. The increase of the secretion of the hormone is observed in the states of hipertiroidismo (illness of Serious, poisonous multinodular goiter and poisonous thyroid adenoma). The values increase the same way for ascent of the concentration of tiroglobulina (it means major fixation capacity) and for increase of the liberation of tiroxina from the thyroid cells (tiroiditis subsharp and tiroiditis of Hashimoto after the radiations).
SKILL OF SECURING
To realize this analysis to be on an empty stomach is not needed.
- It is possible to realize the capture in an appropriate place (consultation, clinic, hospital) but sometimes it is realized in the proper domicile of the patient.
- To realize the capture it is needed of locating an appropriate vein and in general there are used the veins placed in the flexura of the elbow. The person entrusted to take the sample will use sanitary gloves, a needle (with a syringe or pipe of extraction).
- It will put a tortor (tape of gum - latex) in the arm so that the veins retain more blood and turn out to be more visible and accessible.
- It will clean the area of the prick with an antiseptic one and by means of a palpación it will locate the appropriate vein and will gain access to her with the needle. They will release the tortor.
- When the blood flows for the needle the sanitary one will realize an aspiration (by means of the syringe or by means of the application of a pipe with gap).
On having finished the capture, it extracts the needle to itself and the area is pressed with a cotton or similar torunda to favor the coagulation and it will indicate him to itself that flexione the arm and the area pressed with a Band-Aid supports for some hours.
PROBLEMS AND POSSIBLE RISKS
- The securing by means of a prick of the vein can produce certain pain.
- The possible difficulty in finding the appropriate vein can give place to several pricks:
- Appearance of a haematoma (bruise or cardinal) in the extraction area, is due usually to the fact that the vein has not closed well after the later pressure and blood has kept on going out producing this problem. Type Hirudoid can apply an ointment to itself ® or Trombocid ® in the area.
- Inflammation of the vein (phlebitis), sometimes the vein turns out to be shaken, well be for a cause merely physically or why it has become infected. It will have to support the relaxed area a few days and type Hirudoid can apply an ointment to itself ® or Trombocid ® in the area. If the problem persists or appears fever will have to consult it with his doctor.
NORMAL VALUES OF STIMULANT HORMONE OF THE THYROID GLAND IN WHEY
The values of reference of T4 must be established in every laboratory, but generally they range between 4 and 12 µg/dl. His determination is realized for radioinmunoanálisis and also it is possible to quantify for inmunoanálisis of multiplication enzimática (EMIT) and for fluoroinmunoanálisis.
POSSIBLE DIAGNOSES IN ABNORMAL VALUES
It can appear high levels of T4 in whey in:
- Illness of Serious
- Illness of Plummer
- Thyroid poisonous adenoma
- Sharp Tiroiditis
- Ovarian Estruma
- Pregnancy
- Hepatitis
- Congenital Hiperproteinemia
It can appear low levels of T4 in whey in:
- Cretinism
- Surgical eradication
- Mixedema
- Insufficiency hipofisaria
- Shortcoming of Iodine
- Renal insufficiency
- Syndrome of Cushing
- Cirrhosis
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