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 DEFINITION
The drop is a persistent metabolic illness, which produces an increase of the circulating, this uric acid it settles in the joints producing inflammation with pain especially in the feet and the legs. This problem usually collaborates also to the diabetes, obesity and renal illnesses.
CAUSES
The drop originates for an acidic excess of uric in the body, good is for the absence of his elimination for the kidney, for unknown causes, or for an increase in his production, associated with an excess of ingestion of rich food in purinas that are metabolized by the organism to uric acid (guts of animals, seafood and vegetables). The alcohol in excess also increases the uric acid. In any case the alteration of the metabolism is causative of 2/3 you depart from the level of circulating uric acid.
On having increased the uric acid, his deposit takes place, in the shape of sharp glazing, in the joints, especially of low parts of the body (feet and legs). This deposit produces an inflammation of the joints with an intense pain that is called a sharp drop attack. Another part of the glazing is eliminated by the urine in the shape of stones producing renal colics.
If the drop attacks are persistent injuries take place deformantes in the joints, forming the called gouty tofos that produce the injuries of the arthritis gouty chronicle.
This alteration of the metabolism fond of 2/1000 you present yourself.
The relation with other chronic illnesses as there are the obesity, hypertension, hiperlipemia (increase of the fat of the blood) and the diabetes is very frequent, by what the complications of these also appear in this illness (cerebral vascular accidents and heart attacks).
DIAGNOSIS
It is realized by the sharp arthritis clinic with pain and functional powerlessness in a young person, is confirmed by an analysis of the uric acid in the blood, which is high. Sometimes if the arthritis is more persistent an analysis of the liquid is realized sinovial (it is extracted by a needle of the joint) to see if there is uric acid glazing. The Rx of the joint usually shows the gouty tofos in one arthritis cronificada.
TREATMENT
It is necessary to lower the circulating uric acid by means of medicines uricosúricos (that increase the renal elimination of uric acid), and also of drugs that block the uric acid production for the organism (Allopurinol).
In the arthritis attacks gouty the anti-inflammatory not esteroideos (AINEs) is used, principally the Indometacina, since the Aspirin must be avoided in these cases. The colchicina was used like antigouty medicine, but his bad intestinal tolerance occurs rarely contraindicarlo.
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