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 OTHER NAMES
DEFINITION
The GammaGT is an enzyme of hepatic origin that takes part in the amino acids transference across the cellular membranes. Her most is at hepatic level and in the biliary routes.
WHY IS THIS STUDY REALIZED?
It is realized in the context of other hepatic tests (GOT, GPT, bilirrubina, fosfatasa alkaline) and is used to evaluate problems or alterations of the liver. It is very sensitive, especially, in problems of obstruction of the biliary routes. It is the enzyme most sensitive to the hepatic problems produced by the alcohol, the first one rises and it is the most sensitive to the damages produced by him. It usually collaborates to the elevation of the alkaline fosfatasa, except in bony problems in which only the alkaline fosfatasa rises.
SKILL OF ACHIEVEMENT
It is not necessary to be on an empty stomach for this parameter but as it is realized by the same blood sample to determine other biochemical parameters in the laboratory it is better being on an empty stomach to realize all of them of the same blood extraction. It is necessary to bear in mind as well as certain medicines can alter his values, they are raised by the alcohol, the phenobarbital and the fenitoína, and the contraceptive oral ones and the clofibrato can diminish his values. It is possible to realize the capture in an appropriate place (consultation, clinic, hospital) but sometimes it is realized in the proper domicile of the patient.
- To realize the capture it is needed of locating an appropriate vein and in general there are used the veins placed in the flexura of the elbow. The person entrusted to take the sample will use sanitary gloves, a needle (with a syringe or pipe of extraction).
- It will put a tortor (tape of gum - latex) in the arm so that the veins retain more blood and turn out to be more visible and accessible.
- It will clean the area of the prick with an antiseptic one and by means of a palpación it will locate the appropriate vein and will gain access to her with the needle. They will release the tortor.
- When the blood flows for the needle the sanitary one will realize an aspiration (by means of the syringe or by means of the application of a pipe with gap).
- On having finished the capture, it extracts the needle to itself and the area is pressed with a cotton or similar torunda to favor the coagulation and it will indicate him to itself that flexione the arm and the area pressed with a Band-Aid supports for some hours.
- The abstracted blood moves to the analysis laboratory in a special pipe for biochemistry, which contains an anticoagulant product. In general more than 10 milliliters of blood are not usually necessary for a standard battery of biochemical parameters.
PROBLEMS AND POSSIBLE RISKS
- The securing by means of a prick of the vein can produce certain pain.
- The possible difficulty in finding the appropriate vein can give place to several pricks
- Appearance of a haematoma (bruise or cardinal) in the extraction area, is due usually to the fact that the vein has not closed well after the later pressure and blood has kept on going out producing this problem. Type Hirudoid can apply an ointment to itself ® or Trombocid ® in the area.
- Inflammation of the vein (phlebitis), sometimes the vein turns out to be shaken, well be for a cause merely physically or why it has become infected. It will have to support the relaxed area a few days and type Hirudoid can apply an ointment to itself ® or Trombocid ® in the area. If the problem persists or appears fever will have to consult it with his doctor.
NORMAL VALUES OF GAMMA GT
| GammaGT |
Men: 8 to 38 U/L |
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Women: 5 to 27 U/L |
In these values there can be certain differences for the skill or for proper criteria of normality of concrete laboratories, sometimes in the status of values and other times for the units to which one alludes.
EVALUATION OF ABNORMAL RESULTS
The developing GammaGT levels can indicate:
- Alcoholism
- Colestasis (obstruction of the biliary route)
- Cirrhosis
- Hepatitis
- Viral infections (mononucleosis...)
- Congestive heart failure
- Hepatic Isquemia
- Poisonous medicines of the liver
- Hepatic Necrosis
- Hepatic tumor
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