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OTHER NAMES
DEFINITION
The factor reumatoide (FR) is a test that measures the presence and level of the specific IgM against the antibodies abnormal IgG, produced by the lymphocytes of the membrane sinovial, of the joints of persons affected by the Rheumatoid arthritis.
WHY IS THIS STUDY REALIZED?
The Rheumatoid arthritis is a chronic illness, which produces the inflammation of the joints principally of hands and feet. When these antibodies IgG originate and the IgM is fixed, there form inmunocomplejos IgG-IgM that activate the Complement and other inflammatory factors that produce a second time the destruction of the affected joints. By it there is called he an autoimmune illness, since it is the immune system of the individual the one that destroys textiles of the proper body. It is not a specific analysis of this illness, it turns out to be positive in 80 % of the patients with Rheumatoid arthritis, but it can turn out to be negative. Inclusive it can turn out to be positive in other not related illnesses (Systemic Lupus Eritematoso, Syndrome of Sjogren, etc...). In persons of the third age levels raised without clinical aftereffect can appear.
SKILL OF ACHIEVEMENT
To realize this analysis to be on an empty stomach is not needed. It is possible to realize the capture in an appropriate place (consultation, clinic, hospital) but sometimes it is realized in the proper domicile of the patient. To realize the capture it is needed of locating an appropriate vein and in general there are used the veins placed in the flexura of the elbow. The person entrusted to take the sample will use sanitary gloves, a needle (with a syringe or pipe of extraction). It will put a tortor (tape of gum - latex) in the arm so that the veins retain more blood and turn out to be more visible and accessible.
It will clean the area of the prick with an antiseptic one and by means of a palpación it will locate the appropriate vein and will gain access to her with the needle. They will release the tortor.
When the blood flows for the needle the sanitary one will realize an aspiration (by means of the syringe or by means of the application of a pipe with gap).
On having finished the capture, it extracts the needle to itself and the area is pressed with a cotton or similar torunda to favor the coagulation and it will indicate him to itself that flexione the arm and the area pressed with a Band-Aid supports for some hours.
The abstracted blood moves to the analysis laboratory in a special pipe for biochemistry, which contains an anticoagulant product. In general more than 10 milliliters of blood are not usually necessary for a standard battery of biochemical parameters.
PROBLEMS AND POSSIBLE RISKS
- The securing by means of a prick of the vein can produce certain pain.
- The possible difficulty in finding the appropriate vein can give place to several pricks
- Appearance of a haematoma (bruise or cardinal) in the extraction area, is due usually to the fact that the vein has not closed well after the later pressure and blood has kept on going out producing this problem. Type Hirudoid can apply an ointment to itself ® or Trombocid ® in the area.
- Inflammation of the vein (phlebitis), sometimes the vein turns out to be shaken, well be for a cause merely physically or why it has become infected. It will have to support the relaxed area a few days and type Hirudoid can apply an ointment to itself ® or Trombocid ® in the area. If the problem persists or appears fever will have to consult it with his doctor.
NORMAL VALUES OF FACTOR REUMATOIDE (FR)
Normal or NEGATIVE values:
- Minor of 60 Or / ml (for nefelometría).
- Minor title of 1:80 (method of agglutination)
In these values there can be very small differences for the skill or for proper criteria of normality of concrete laboratories, sometimes in the status of values and other times for the units to which one alludes.
EVALUATION OF THE ABNORMAL RESULTS
There can turn out to be POSITIVE the Factor Reumatoide (FR) in:
- Rheumatoid arthritis
- Dermatomiositis
- Escleroderma
- Chronic hepatitis
- Chronic viral infection
- Glandular fever
- Leukemia
- Lupus Eritematoso Sistémico
- Syndrome of Sjogren
- Syndrome Nefrótico
- Tuberculosis
TO SEE ALSO
WHAT DOCTOR CAN TREAT ME?
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