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DENOMINATION
- CPK,
- Creatininfosfoquinasa,
- Creatininfosfoquinasa in blood.
DEFINITION
The creatininfosfoquinasa is an enzyme that is principally in the heart, in the brain and in the skeletal muscles. When it turns out to be high it is because these textiles have incurred some loss.
WHY IS THE ANALYSIS REALIZED?
The appearance of CPK raised in the whey suggests injuries in the heart in the brain or in the skeletal muscles. Depending on the isoenzima of high CPK we can differ what the affected textile is.
It is used to be able to diagnose inflammatory illnesses of the muscles (dermatomiositis, polimiositis), to diagnose a cardiac infarction, or to discover bearers of the muscular dystrophy of Duchenne.
In case of cardiac infarction the curve of his level in blood can offer information of the evolution of the produced cardiac damage and his evolution.
To assure the reliability of the results it has to of doing to him the determination of the isoenzimas that see less affected by the variables of medicines and traumatism that the measurement of entire CPK.
PROCEDURE OF SECURING
To realize this analysis to be on an empty stomach is not needed. They can turn altered the values of CPK if there have been realized intramuscular injections, muscular traumatism, recent interventions of surgery, or intense or long exercise. There are medicines that the level of the CPK can raise in whey: Anfotericina B, ampicilina, anesthetic, anticoagulants, aspirin, clofibrato, dexametasona, furosemida, morphine.
It is possible to realize the capture in an appropriate place (consultation, clinic, hospital) but sometimes it is realized in the proper domicile of the patient. To realize the capture it is needed of locating an appropriate vein and in general there are used the veins placed in the flexura of the elbow. The person entrusted to take the sample will use sanitary gloves, a needle (with a syringe or pipe of extraction). It will put a tortor (tape of gum - latex) in the arm so that the veins retain more blood and turn out to be more visible and accessible. It will clean the area of the prick with an antiseptic one and by means of a palpación it will locate the appropriate vein and will gain access to her with the needle. They will release the tortor. When the blood flows for the needle the sanitary one will realize an aspiration (by means of the syringe or by means of the application of a pipe with gap). On having finished the capture, it extracts the needle to itself and the area is pressed with a cotton or similar torunda to favor the coagulation and it will indicate him to itself that flexione the arm and the area pressed with a Band-Aid supports for some hours.
The abstracted blood moves to the analysis laboratory in a special pipe for biochemistry, which contains an anticoagulant product. In general more than 10 milliliters of blood are not usually necessary for a standard battery of biochemical parameters.
PROBLEMS AND POSSIBLE RISKS
- The securing by means of a prick of the vein can produce certain pain.
- The possible difficulty in finding the appropriate vein can give place to several pricks
- Appearance of a haematoma (bruise or cardinal) in the extraction area, is due usually to the fact that the vein has not closed well after the later pressure and blood has kept on going out producing this problem. Type Hirudoid can apply an ointment to itself ® or Trombocid ® in the area.
- Inflammation of the vein (phlebitis), sometimes the vein turns out to be shaken, well be for a cause merely physically or why it has become infected. It will have to support the relaxed area a few days and type Hirudoid can apply an ointment to itself ® or Trombocid ® in the area. If the problem persists or appears fever will have to consult it with his doctor.
NORMAL VALUES OF CPK IN WHEY
Normal levels of CPK in whey: 24 to 194 Or / ml
In these values there can be small differences for the skill or for proper criteria of normality of concrete laboratories, sometimes in the status of values and other times for the units to which one alludes.
EVALUATION OF ABNORMAL RESULTS
The developing CPK levels in the blood can indicate:
- Convulsions
- Delirium tremens
- Dermatomiosistis
- Muscular dystrophy
- Hipotiroidismo
- Cardiac infarction
- Pulmonary infarction
- Alcoholic Miopatía
- Pericarditis
- Polimiositis
- Traumatism of the central nervous system
TO SEE ALSO
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