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 DENOMINATION
- Acetilcolinesterasa,
- Colinesterasa in red globules,
- Seudocolinesterasa,
- Colinesterasa in plasma,
- Butilcolinesterasa.
DEFINITION
The analysis of the colinesterasa in the whey consists of the study of the enzymes of acetilcolinesterasa ó colinesterasa of the red globules and of the seudocolinesterasa or colinesterasa of the plasma. This all enzymes act decomposing the acetilcolina.
The acetilcolina is a molecule that is used by the nervous cells to transmit nervous stimuli.
WHY IS THE ANALYSIS REALIZED?
The study of the colinesterasa is realized in the preoperative control since during the anesthesia it is used succinilcolina, that is a disabling agent. If the colinesterasa does not work in an individual the succinilcolina is not eliminated and there can be serious complications (muscular palsy and apnea) for revertir his effect after the anesthesia. It is usually a congenital defect, in which the proper person or his relatives already had problems of delay in recovering of an anesthesia. Also it is used to evaluate the intense exhibition to insecticides organofosfatos, which unactivate the colinesterasas, and the level of these enzymes serves like an indicator of the exhibition and of the risks of his toxicity.
Sometimes it can be an indicator of certain hepatic illnesses.
PROCEDURE OF SECURING
To realize this analysis to be on an empty stomach is not needed. The pregnancy can diminish the values of colinesterasa. Also medicines can diminish his true values, the atropina, the caffeine, the codeine, the estrogen, the sulfate of morphine, the nesotigmina, the contraceptive ones, the teofilina and the vitamin K. It is possible to realize the capture in an appropriate place (consultation, clinic, hospital) but sometimes it is realized in the proper domicile of the patient. To realize the capture it is needed of locating an appropriate vein and in general there are used the veins placed in the flexura of the elbow. The person entrusted to take the sample will use sanitary gloves, a needle (with a syringe or pipe of extraction). It will put a tortor (tape of gum - latex) in the arm so that the veins retain more blood and turn out to be more visible and accessible. It will clean the area of the prick with an antiseptic one and by means of a palpación it will locate the appropriate vein and will gain access to her with the needle. They will release the tortor.
When the blood flows for the needle the sanitary one will realize an aspiration (by means of the syringe or by means of the application of a pipe with gap).
On having finished the capture, it extracts the needle to itself and the area is pressed with a cotton or similar torunda to favor the coagulation and it will indicate him to itself that flexione the arm and the area pressed with a Band-Aid supports for some hours. The abstracted blood moves to the analysis laboratory in a special pipe for biochemistry, which contains an anticoagulant product. In general more than 10 milliliters of blood are not usually necessary for a standard battery of biochemical parameters.
PROBLEMS AND POSSIBLE RISKS
- The securing by means of a prick of the vein can produce certain pain.
- The possible difficulty in finding the appropriate vein can give place to several pricks.
- Appearance of a haematoma (bruise or cardinal) in the extraction area, is due usually to the fact that the vein has not closed well after the later pressure and blood has kept on going out producing this problem. Type Hirudoid can apply an ointment to itself ® or Trombocid ® in the area.
- Inflammation of the vein (phlebitis), sometimes the vein turns out to be shaken, well be for a cause merely physically or why it has become infected. It will have to support the relaxed area a few days and type Hirudoid can apply an ointment to itself ® or Trombocid ® in the area. If the problem persists or appears fever will have to consult it with his doctor.
NORMAL VALUES OF COLINESTERASA
The normal values of colinesterasa are between 8 and 18 Or / ml (units for milliliter).
MEANING OF THE ABNORMAL VALUES
The decrease in the colinesterasa levels can be for:
- Congenital shortcoming
- Poisoning for insecticides organofosfatos
- Hepatic illnesses
- Sharp infection
- Chronic undernourishment
- Metástasis
- Myocardium infarction
The developing colinesterasa levels it can be for:
- Diabetes
- Hiperlipemia
- Nefrosis
- Reticulosis
TO SEE ALSO
WHAT DOCTOR CAN TREAT ME?
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DENOMINATION 
