Tuotromedico: Antidepressants

Frequent questions

He asks the doctor

Beginning

TO CONSULT

The psychotropic drugs used in the treatment of the depression include (to See TABLE):

antidepressants tric�clicos

antidepressants tetrac�clicos

inhibiting of the monkey - aminoxidasa (IMAO), including to the antidepressants IT RHYMES (moclobemida), of selective and reversible action on the monoaminoxidasa A.

inhibiting of the rereception of serotonina and other antidepressants of "new generation": fluvoxamina, trazodona, fluoxetina, paroxetina, sertralina, citalopram, etc.

you go out of lithium, especially in the depressions of the bipolar disorders (manic depressive psychosis).

The rule of advisable medication consists of initiating the treatment with a low dose (for example, 50-75 mg/d�a for medicines type imipramina, amitriptilina or maprotilina), increasing it quickly up to reaching the maximum dose (150-200 mg/d�a) during the second week of treatment.

This maximum dose supports 4 � 6 weeks, even if a notable clinical improvement has been obtained in advance.

Then the dose diminishes gradually between the sixth one and twelfth weeks of treatment, being able to interrupt this one or continue it, according to the case, according to grade of reference, persistence of motivations, etc. A small it is necessary to continue the treatment, with decreasing doses, up to 6 months.

The improvement is usually clear during the third week and reaches his most effective grade between the fourth one and the country house weeks.

Other therapeutic employees are:

the remedies of deprivation of sleep.

therapeutics electroconvulsionante, that keeps on supporting his indications in the field of certain psychotic depressions or with serious ideas of suicide. Nevertheless, his use has remained much restricted in the last years, thanks to the more and more specific action of the said psychotropic drugs.

ANTIDEPRESSING MEDICINES

Nature

Medicines

Registered trade name �

Average dose

Tric�clicos	Imipramina	Tofranil	75-150 mg/d�a p.o
	Clomipramina	Anafranil	75-150 mg/d�a p.o
	Amitriptilina	Tryptizol	75-150 mg/d�a p.o
	Trimeprimina	Surmontil	75-150 mg/d�a p.o
	Nortriptilina	Martimil, Paxtibi	75-150 mg/d�a p.o
	Doxepina	Sinequan	140-210 mg/d�a p.o.
	Lofepramina	Deftan	70-140 mg/d�a p.o.
	Amineptina	Survector	100-200 mg/d�a p.o.
	Quinupramina	Quinuprine	5-7,5 mg/d�a p.o.

Tetrac�clicos	Maprotilina	Ludiomil	75-150 mg/d�a p.o.
	Mianserina	Lantanon	30-90 mg/d�a p.o.

IMAO ^*	Iproniazida	Iproniazida	50-75 mg/d�a p.o.
	Nialamida	Niamid	100-200 mg/d�a p.o.
	Fenelzina	Nardelzine	30-45 mg/d�a p.o.
	Tranilcipromina	Parnate	20-40 mg/d�a p.o.
	Moclobemida (HEAP)	Manerix	150-300 mg/d�a p.o.

Selective Serotonin�rgicos	Fluvoxamina	Dumirox	100-200 mg/d�a p.o.
	Fluoxetina	Prozac, Reneuron, Adofen	20-60 mg/d�a p.o.
	Paroxetina	Seroxat, Motivates, Frosinor	20-40 mg/d�a p.o.
	Sertralina	Aremis, Besitran	50-100 mg/d�a p.o.
	Citalopram	Seropram

Others	Protirelina	TRH-Prem	2-20 mg/d�a p.o.
		TRH-UCB	6-12 mg/d�a p.o.
	L-5-HO-tript�fano	Telesol, Cincofarm	200-600 mg/d�a p.o.
	Pirlindol	Lifril	150-200 mg/d�a p.o.
	Tradozona	Deprax	100-300 mg/d�a p.o.
			100-200 mg/d�a i.v.
	Minaprina	Isopulsan	100-150 mg/d�a p.o.

* IMAO = Inhibiting of the Mono-Amino-Oxidasa

WHAT DOCTOR CAN TREAT ME?

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Update: June, 2009

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