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ANEMIAS OF THE NEWBORN BABY
ANEMIAS INCOMPATIBILITY WITH THE BLOOD TYPE INCOMPATIBILITY WITH THE RH PREVENTION TO CONSULT

ANEMIAS

The hemoglobin is the ferric pigment that the red globules take inside, by means of which they distribute the oxygen in the textiles of the organism. The red globules in normal conditions live through approximately 3 months, after which they are destroy you in the spleen. An anemia is the situation in which the number of red globules (and therefore the concentration of circulating hemoglobin) is disminuído. There are many causes of anemia in the newborn babies.

Physiological anemia of the nursing one. During 2 ó the first 3 months of life, the circulating hemoglobin diminishes gradually, since the red globules of the newborn baby have a minor life expectancy (90 days, instead of 120 days of life in the adult). This situation is normal and she does not need treatment.

Anemia of the prematurity. The speed of descent of the hemoglobin and his rock bottom are more pronounced in the premature babies. This picture owes fundamentally at the highest speed of growth of the premature babies. Also, the blood extracted to the nursing sick premature babies with analytical ends exaggerates moreover the red blood corpuscles fall. The lowest value of concentration of the hemoglobin is reached usually after approximately 6 weeks in the premature babies. There are no studies that they demonstrate that either the transfusions, or the treatment with iron, turn out to be beneficial in the anemia of the prematurity.

Anemia ferropénica of the nursing one. It owes to a shortcoming of iron, without which it is not possible to make the hemoglobin of the red globules. The newborn babies who receive artificial formulae must receive supplements of iron (2 mg of elementary / kg / day iron). Otherwise, they will use his iron reservations and will exhaust them after 10 to 14 weeks, if they are premature, and after approximately 5 months if they went to term.

INCOMPATIBILITY WITH THE GROUP SANGINEO (ABO)

It happens when the blood type of the mother is O and that of the newborn baby is A or B. The called illness takes place hemolítica: the red globules of the newborn baby are destroyed quickly and an anemia takes place. The principal clinical problem is the development of a significant hiperbilirrubinemia after the birth, since the liberated hemoglobin of the red globules destroy to you it turns in bilirrubina (to See "JAUNDICE NEONATAL AND FOTOTERAPIA"). Usually, antibodies are anti A or anti-B in the whey of the newborn baby (indirect test of positive Coombs).

INCOMPATIBILITY RHESUS (RH)

It happens when a woman Rh negativa has a Rh-Positive fetus. Some (incompatible) fetal red blood corpuscles cross the afterbirth and induce an immune answer of maternal antibodies, which later cross the afterbirth and go on to the fetus, in which they provoke illness hemolítica: the red globules of the newborn baby are destroyed quickly and an anemia takes place.

The first immunization can happen for an abortion or a pregnancy with Rh-Positive fetus. The gravity increases in the following pregnancies and each of the later newborn babies has more probabilities of being affected. The fetuses more seriously affected develop an intense anemia (eritroblastosis fetal) with fetal death intrauterina, or they are born with a fetal dropsy (distension generalized). Shortly after the birth, the patients usually develop the serious one hiperbilirrubinemia due to the effect hemolítico continuously of the antibodies anti-Rh that crossed the afterbirth.

PREVENTION

    Before the childbearing:
  • Determination in FETAL blood of red globules and hemoglobin and of the blood type, as well as a test of direct Coombs.
    During the childbearing:
  • It is necessary to monitor the beats of the fetus and, if signs of fetal suffering appear or the child is affected seriously, one will proceed to realize a Cesarean section.
    After the childbearing:
  • In all the newborn babies of mother Rh negativa there must be done an immediate analysis of the blood of the drawstring, in order to determine the blood type of the fetus, and a test of direct Coombs. If the newborn baby is a Rh-Positive and the test of direct Coombs is positive, it will decide if anemia exists and the bilirrubina level will measure itself in the blood of the drawstring.
  • To know the risk of suffering the illness in the second pregnancy, antibodies determinations are realized antid-D in the mother at the age of 12-16 weeks, 28-32 and 36 weeks of the pregnancy.

If the tests are negative, a gammaglobulina anti-D dose will be administered about 28 weeks of the pregnancy. This vaccine will destroy the fetal red globules that have entered his blood stream before his body has had the opportunity to create antibodies.
If the newborn baby is Rh + a new dose will be administered at 48-72 hours after the childbearing.
If the antibodies levels anti-D are superior to 1/16, a series of control panel must be realized to see if there is fetal affectation, and if it is suspected to realize amniocentesis to see the levels of bilirrubina of the amniotic liquid. Normally it realize periodic control panel to verify that they do not increase and to try to take the pregnancy to term.
If there are present antibodies and anemia is detected in the fetus, a blood transfusion is realized to replace the blood supply of the fetus with blood negative Rh, which will not be damaged by the antibodies that his body has created.
The transfusion is administered across the umbilical cord while the fetus is still in the womb, although depending on the affectation grade, and since this is a procedure of certain risk, it can prefer to induce the childbearing work before time, so that the blood transfusion could be realized after the birth of the baby.

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Writing: Medical equipment   Update: June, 2009


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